Medium weight,warm enough even in the coldest winter nights,provides warmth for year-round comfort
This All Season BestSheets Comforter Set Will Add to the Perfect Touch to Your Bedroom Décor and Is a Perfect Gift to a Loved One!
Machine Wash in Cold/Warm Water, Delicate Cycle with Mild Detergent, No Bleach, Tumble Dry on Low, Remove Immediately at end of Cycle
BestSheets brings you the Luxury Decorative Pinch Pleated Comforter Set! The Set has Extraordinary Colors that come in Different Sizes which will add a Lovely Touch to Your Bedroom Decor. Our Bedding Set is made out of 100% Egyptian Cotton of Solid Pattern. Comfort, Quality and Opulence Distinguishes Our Unique Bedding from the Rest and Sets it in a Higher Class. ORDER TODAY and ENJOY Our Luxurious Pinch Pleated Comforter Set from BestSheets.
2020 Impact Factor: 9.941Submission > Acceptance: 52 days
No. 106 (11)
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Transducin β-like protein 1 (TBL1) plays a crucial role in controlling the stability of regulatory proteins involved in cell proliferation and autophagy induction. This study revealed that, unlike normal B cells, diffuse large B-cell lymphoma cells express abundant levels of TBL1 and its overexpression correlates with poor clinical outcome. Targeting TBL1 promoted lymphoma cell death in vitro and in vivo. These results provide the rationale for targeting TBL1 as a novel therapeutic strategy in diffuse large B-cell lymphoma.
The authors of this study developed a single-chain antibody that targets a shear gradient-specific conformation of von Willebrnad factor (VWF). In vitro studies showed that this antibody specifically reduces VWF-GPIbα binding and thrombus formation at sites of shear rate gradients but does not block platelet deposition and aggregation under constant shear rate. This characteristic places the antibody in a new class of antiplatelet therapy for selective blockade of pathological thrombus formation while maintaining normal hemostasis.
A 26-year-old female developed vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous thrombosis and bi-hemispheric hemorrhage following the first dose of the ChAdOx1 nCoV-19 vaccine. The treatment protocol, based on intravenous immunoglobulins, dexamethasone and argatroban was successful with almost complete clinical, laboratory and radiological response. This experience supports the application of an early and multidisciplinary therapeutic approach in cases of VITT, with the possibility of avoiding deaths and obtain a resolution of the syndrome.
This retrospective study compared the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) in 23 patients with hematologic malignancies transplanted from non-sibling fully matched related donors to that of patients who underwent conventional haplo-HSCT. Subjects transplanted from fully matched related donors showed trends to a higher relapse rate and lower cumulative incidence of grade II-IV acute graft-versus-host disease, but overall survival was similar. The authors concluded that individualized adjustment of the immunosuppressive treatment is reasonable for this category of patients.